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Mechanisms of embryo-maternal

Coordinator: Prof. Dr. Eckhard Wolf, Genzentrum der LMU-München

Unit 478

Selected Publications:
  1. Bauersachs S, Blum H, Mallok S, Wenigerkind H, Rief S, Prelle K, Wolf E (2003) Regulation of ipsilateral and contralateral bovine oviduct epithelial cell function in the post-ovulation period - a transcriptomics approach. Biol Reprod 68, 1170-1177

  2. Bauersachs S, Rehfeld S, Ulbrich S, Mallok S, Prelle K, Wenigerkind H, Einspanier R, Blum H, Wolf E (2004) Monitoring gene expression changes in bovine oviduct epithelial cells during the oestrous cycle. J Mol Endocrinol 32, 449-466

  3. Bauersachs S, Ulbrich SE, Gross K, Schmidt SEM, Meyer HHD, Einspanier R, Wenigerkind H, Vermehren M, Blum H, Sinowatz F, Wolf E (2005) Gene expression profiling of bovine endometrium during the oestrous cycle: detection of molecular pathways involved in functional changes. J Mol Endocrinol 34, 889-908

  4. Bauersachs S, Ulbrich SE, Gross K, Schmid SEM, Meyer HHD, Wenigerkind H, Vermehren M, Sinowatz F, Blum H, and Wolf E (2006) Embryo-induced transcriptome changes in bovine endometrium reveal species-specific and common molecular markers of uterine receptivity. Reproduction 132, 319-331

  5. Berendt FJ, Fröhlich T, Schmidt SEM, Reichenbach HD, Wolf E, Arnold GJ (2005) Holistic differential analysis of embryo-induced alterations in the proteome of bovine endometrium in the pre-attachment period. Proteomics 5, 2551-2560

  6. Boelhauve M, Sinowatz F, Wolf E, Paula-Lopes FF (2005) Maturation of bovine oocytes in the presence of leptin improves development and reduces apoptosis of in vitro-produced blastocysts. Biol Reprod 73, 737-744

  7. Einspanier R, Ulbrich S, Schönfelder M (2004) Communication within the female genital tract: analysis of paracrine mediators in the reproductive epithelium. Andrologia 36, 130-132

  8. Ewerling S, Hofmann A, Klose R, Weppert M, Brem G, Rink K, Pfeifer A, Wolf E (2006) Evaluation of laser-assisted lentiviral transgenesis in bovine. Transgenic Res (in press)

  9. Herrler A, von Rango U, Beier HM (2003) Embryo-maternal signalling: how the embryo starts talking to its mother to accomplish implantation. Reprod Biomed Online 6, 244-256

  10. Hiendleder S, Bauersachs S, Boulesteix A, Blum H, Arnold GJ, Fröhlich T, Wolf E (2005) Functional genomics: tools for improving farm animal health and welfare. Rev Sci Tech 24, 355-377

  11. Hofmann A, Kessler B, Ewerling S, Weppert M, Vogg B, Ludwig H, Stojkovic M, Boelhauve M, Brem G, Wolf E, Pfeifer A (2003) Efficient transgenesis in farm animals by lentiviral vectors. EMBO Rep 4, 1054-1060

  12. Hofmann A, Zakhartchenko V, Weppert M, Sebald H, Wenigerkind H, Brem G, Wolf E, Pfeifer A (2004) Generation of transgenic cattle by lentiviral gene transfer into oocytes. Biol Reprod 71, 405-409

  13. Klein C, Bauersachs S, Ulbrich SE, Einspanier R, Meyer HH, Schmidt SE, Reichenbach HD, Vermehren M, Sinowatz F, Blum H, Wolf E. (2006) Monozygotic twin model reveals novel embryo-induced transcriptome changes of bovine endometrium in the preattachment period. Biol Reprod 74, 253-264

  14. Kölle S, Stojkovic M, Boie G, Wolf E, Sinowatz F (2003) Growth hormone-related effects on apoptosis, mitosis and expression of connexin 43 in IVM cumulus-oocyte-complexes. Biol Reprod 68, 1584-1589

  15. Kölle S, Stojkovic M, Reese S, Reichenbach HD, Wolf E, Sinowatz F (2004) Effects of growth hormone on the ultrastructure of bovine preimplantation embryos. Cell Tissue Res 317, 101-108

  16. Machado SA, Reichenbach H-D, Weppert M, Wolf E, Gonçalves PBD (2006) The variability of ovum pick-up response and in vitro embryo production using monozygotic twins. Theriogenology 65, 573-583

  17. tojkovic M, Krebs O, Kölle S, Prelle K, Assmann V, Zakhartchenko V, Sinowatz F, Wolf E (2003) Developmental regulation of hyaluronan-binding protein (RHAMM/IHABP) expression in early bovine embryos. Biol Reprod 68, 60-66

  18. Ulbrich SE, Rehfeld S, Bauersachs S, Wolf E, Rottmayer R, Hiendleder S, Vermehren M, Sinowatz F, Meyer HH, Einspanier R (2006) Region-specific expression of nitric oxide synthases in the bovine oviduct during the oestrous cycle and in vitro. J Endocrinol 188, 205-213

  19. Ulbrich SE, Kettler A, Einspanier R (2003) Expression and localization of estrogen receptor alpha, estrogen receptor beta and progesterone receptor in the bovine oviduct in vivo and in vitro. J Steroid Biochem Mol Biol 84, 279-289

  20. Ulbrich SE, Schoenfelder M, Thoene S, Einspanier R (2004) Hyaluronan in the bovine oviduct - modulation of synthases and receptors during the estrous cycle. Mol Cell Endocrinol 214, 9-18

  21. Wolf E, Arnold GJ, Bauersachs S, Beier HM, Blum H, Einspanier R, Fröhlich T, Herrler A, Hiendleder S, Kölle S, Prelle K, Reichenbach H-D, Stojkovic M, Wenigerkind H, Sinowatz F (2003) Embryo-maternal communication in bovine – strategies for deciphering a complex cross-talk. Reprod Domest Anim 38, 276-289